- There are around 4,000 new thyroid cancer cases in the UK every year
- Thyroid cancer is the 20th most common cancer in the UK, accounting for 1% of all new cancer cases
- Thyroid cancer primarily develops from two types of cells: follicular cells (which produce and store the hormones T3 and T4 and the protein thyroglobulin) and parafollicular cells (which produce the hormone calcitonin and help control calcium levels in the body).
Thyroid Cancer
Thyroid cancer develops when cells grow and divide abnormally in the thyroid, a small butterfly-shaped gland at the front of the neck.
Papillary thyroid cancer
Papillary thyroid cancer is the most common type of thyroid cancer, making up 70-80% of all cases. It develops from the follicular cells and tends to grow slowly to areas such as surrounding lymph nodes.
Follicular thyroid cancer
Follicular thyroid cancer makes up 15-25% of thyroid cancer cases and develops from follicular cells. Although it is unlikely to spread to the lymph nodes, it can spread to other parts of the body. Hürthle cell carcinoma is a rare and more aggressive type of follicular thyroid cancer.
Medullary thyroid cancer
Medullary thyroid cancer develops from the parafollicular cells (C-cells) and makes up 4% of all thyroid cancer cases. It can be passed down through families (hereditary thyroid cancer).
Anaplastic thyroid cancer
Anaplastic thyroid cancer is a rare and fast-growing type of thyroid cancer, which develops from papillary or follicular thyroid cancer.
Papillary and follicular thyroid cancer
Only Stage I and Stage II apply to those under 55 years of age.
Stage I
The cancer is no larger than 4 cm and confined to the thyroid. For those under 55, the cancer may be any size and might or might not have spread to nearby lymph nodes.
Stage II
The cancer is no larger than 4 cm across and confined to the thyroid, but has spread to nearby lymph nodes. For those under 55, the cancer may be any size and has spread to other areas of the body such as distant lymph nodes, internal organs or bone.
Stage III
The cancer may be any size and has spread to nearby tissue such as the larynx, trachea or oesophagus. It might or might not have spread to nearby lymph nodes.
Stage IVA
The cancer may be any size and has spread extensively beyond the thyroid toward the spine or into nearby large blood vessels. It might or might not have spread to nearby lymph nodes.
Stage IVB
The cancer is any size and might or might not have spread to nearby lymph nodes, but has spread to distant areas of the body such as lymph nodes, internal organs or bones.
Anaplastic thyroid cancer
All anaplastic thyroid cancers are considered Stage IV.
Stage IVA
The cancer is any size and confined to the thyroid.
Stage IVB
The cancer is any size and confined to the thyroid, but has spread to nearby lymph nodes. Alternatively, the cancer is any size and has grown into the strap muscles around the thyroid, but might or might not have spread to nearby lymph nodes.
Stage IVC
The cancer is any size and might or not have spread to nearby lymph nodes, but has spread to distant areas of the body such as lymph nodes, internal organs or bone.
Medullary thyroid cancer
Stage I
The cancer is no larger than 2 cm and confined to the thyroid.
Stage II
The cancer is no larger than 4 cm across and confined to the thyroid. Alternatively, the cancer is larger than 4 cm and confined to the thyroid, or any size and growing outside of the thyroid but not involving nearby structures.
Stage III
The cancer is any size and may be growing outside of the thyroid but not involving nearby structures. It has spread to lymph nodes in the neck.
Stage IVA
The cancer is any size and has grown into nearby tissues in the neck, such as the larynx, trachea or oesophagus. It might or might not have spread to nearby lymph nodes. Alternatively, the cancer is any size and might be growing outside of the thyroid, but has spread to certain lymph nodes in the neck.
Stage IVB
The cancer is any size and has grown toward the spine or into nearby large blood vessels, but might or might not have spread to nearby lymph nodes.
Stage IVC
The cancer is any size and might have grown into nearby structures or lymph nodes, but has spread to distant areas of the body such as the liver, lung, bone or brain.
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